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Alert Number 184

HuMax-CD20: Belt, Suspenders — and Cummerbund

Date: August 12, 2006

Our recent article on how HuMax-CD20 works (A Smarter Monoclonal on Trial) was admittedly a “cartoon” version, but we were careful to check our facts with several heavy-weight experts before we published our review. I continue to think this new anti-CD20 will play an important role in the treatment of CLL patients.

Our ongoing dialogue with our advisory board has raised an additional issue worth noting, one that falls into the category of potential risk - especially in the context of the heavily pre-treated and refractory patients recruited for the Phase-3 HuMax-CD20 trial, patients who might also be significantly immune compromised going into this trial. If, like me, you like being safe rather than sorry, you will want to read our latest article: HuMax-CD20: Risks and Rewards.

Be well,


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