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Alert Number 104

17-AAG: A Brand New Clinical Trial

Date: June 24, 2005

In an article we published 2 days ago I said I was going to look into this Hsp90 inhibition business (using an antibiotic called 17-AAG) that might turn out to be a good for us. Well, here is the hot-off-the-presses scoop on the subject. We have just published (see 17AAG Clinical Trial) our review of a brand new-yet-to-be-published article in Blood by a couple of our favorite researchers, Dr. Kipps and Dr. Castro of UCSD, as well as a very interesting multi-center clinical trial using this drug for poor prognosis / late stage CLL patients. The trial is recruiting volunteers even as you read this article. I have a hunch this might be an interesting one. I like the science and the design of this clinical trial. If you are pondering therapy choices, this is one you should check out for yourself.

How is that for service — fast enough for you?

Be well,


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